5 EASY FACTS ABOUT PKRRATING DESCRIBED

The interfacial residues are very conserved amongst eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements show the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations support a design where activating RNA serves for a scaffold to bind many PKR monomers, rising the area focus to bo

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